RBM22 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RBM22 Polyclonal antibody
Uniprot No.：

Q9NW64
基因名：

RBM22
别名：

Cwc2 antibody; FLJ10290 antibody; fSAP47 antibody; Functional spliceosome associated protein 47 antibody; Pre mRNA splicing factor RBM22 antibody; Pre-mRNA-splicing factor RBM22 antibody; RBM 22 antibody; rbm22 antibody; RBM22_HUMAN antibody; RNA binding motif protein 22 antibody; RNA-binding motif protein 22 antibody; ZC3H16 antibody; Zinc finger CCCH domain containing protein 16 antibody; Zinc finger CCCH domain-containing protein 16 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Pre-mRNA-splicing factor RBM22 protein (2-250AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
基因功能参考文献：
1. Cwc2/RBM22-RNA contacts are functionally important. PMID: 22246180
2. ALG-2 alone evenly distributed within the cell, whereas in the presence of RBM22 the two proteins co-localized within the nucleus. PMID: 17045351
亚细胞定位：

Nucleus. Cytoplasm.
蛋白家族：

SLT11 family
数据库链接：

HGNC: 25503

OMIM: 612430

KEGG: hsa:55696

STRING: 9606.ENSP00000199814

UniGene: Hs.713564