RASSF3 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RASSF3 Polyclonal antibody
Uniprot No.：

Q86WH2
基因名：

RASSF3
别名：

MGC119194 antibody; MGC119195 antibody; MGC119197 antibody; Ras association (RalGDS/AF 6) domain family 3 antibody; Ras association domain containing protein 3 antibody; Ras association domain-containing protein 3 antibody; RASF3_HUMAN antibody; Rassf3 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Ras association domain-containing protein 3 protein (2-109AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

基因功能参考文献：
1. low expression is associated with malignant phenotypes in non-small cell lung cancer patients PMID: 24246507
2. Taken together, these findings indicate that the RASSF3 promoter rs6581580 T>G SNP is potentially functional, modulating susceptibility to SCCHN among non-Hispanic whites. PMID: 24295637
3. hypermethylation-induced RASSF3 silencing plays an important role in the tumorigenesis of pituitary somatotroph adenomas. PMID: 23555615
4. tumor suppressor activity of RASSF3, which occurs through p53 stabilization and regulation of apoptosis and the cell cycle. PMID: 22593196
5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
6. Mammary tumor incidence in bi-transgenic mice is delayed, suggesting that transgenic Rassf3 may influence mammary tumor incidence in transgenic mice PMID: 19148488
7. The presence of a Ras association domain common to NORE1,RASSF1, and RASSF3 suggests their possible involvement inRas-like signaling pathways. PMID: 11965544
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亚细胞定位：

Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial cells.
组织特异性：

Widely expressed.
数据库链接：

HGNC: 14271

OMIM: 607019

KEGG: hsa:283349

STRING: 9606.ENSP00000336616

UniGene: Hs.643605