RASA2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RASA2 Polyclonal antibody
Uniprot No.：

Q15283
基因名：

RASA2
别名：

GAP1m antibody; GTPase activating protein of RAS antibody; Ras GTPase activating protein 2 antibody; Ras GTPase-activating protein 2 antibody; RAS p21 protein activator 2 antibody; Rasa2 antibody; RASA2_HUMAN antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Ras GTPase-activating protein 2 protein (609-850AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
基因功能参考文献：
1. Recurrent inactivating RASA2 mutations are associated with melanoma. PMID: 26502337
2. GAP1m is a Ras GAP that switches off Ras signalling. GAP1m undergoes a plasma membrane association following growth factor stimulation of PI 3-kinase as a result of its PH domain binding to phosphatidylinositol 3,4,5-trisphosphate. PMID: 10074452
亚细胞定位：

Cytoplasm. Cytoplasm, perinuclear region.
数据库链接：

HGNC: 9872

OMIM: 601589

KEGG: hsa:5922

STRING: 9606.ENSP00000286364

UniGene: Hs.655941