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RALY Antibody, FITC conjugated

  • 中文名称:
    RALY兔多克隆抗体, FITC偶联
  • 货号:
    CSB-PA892332LC01HU
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) RALY Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RALY
  • 别名:
    Autoantigen p542 antibody; Heterogeneous nuclear ribonucleoprotein C-like 2 antibody; hnRNP associated with lethal yellow protein homolog antibody; hnRNP core protein C-like 2 antibody; MGC117312 antibody; P542 antibody; RALY antibody; RALY_HUMAN antibody; RNA binding protein (autoantigenic hnRNP associated with lethal yellow) antibody; RNA binding protein (autoantigenic) antibody; RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)) antibody; RNA-binding protein Raly antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human RNA-binding protein Raly protein (254-306AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    FITC
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP).
  • 基因功能参考文献:
    1. hnRNP RALY regulates PMID: 28972179
    2. RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells PMID: 28733251
    3. RALY is a poly-U binding protein and as a regulator of H1FX and ANXA1 in mammalian cells. PMID: 28379492
    4. People with lower level of RALYL expression had a poorer survival rate. PMID: 22994768
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    RRM HNRPC family, RALY subfamily
  • 组织特异性:
    Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
  • 数据库链接:

    HGNC: 15921

    OMIM: 614663

    KEGG: hsa:22913

    STRING: 9606.ENSP00000246194

    UniGene: Hs.136947