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RABIF Antibody, Biotin conjugated

  • 中文名称:
    RABIF兔多克隆抗体, Biotin偶联
  • 货号:
    CSB-PA019236LD01HU
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) RABIF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    RABIF
  • 别名:
    RABIF antibody; MSS4 antibody; RASGRF3 antibody; Guanine nucleotide exchange factor MSS4 antibody; Rab-interacting factor antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Guanine nucleotide exchange factor MSS4 protein (1-123AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Biotin
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport.
  • 基因功能参考文献:
    1. The findings reveal a crucial role of RABIF in vesicle transport and establish RABIF as a Rab-stabilizing holdase chaperone, a previously unrecognized mode of Rab regulation independent of its GDP-releasing activity. PMID: 28894007
    2. The expression levels of cellular Mss4 mRNA and protein are rapidly changed in response to a broad range of extracellular stress stimuli. PMID: 22495352
    3. MSS4 modulates Rab15 activity in early endocytosis PMID: 12105226
  • 蛋白家族:
    DSS4/MSS4 family
  • 组织特异性:
    Ubiquitous.
  • 数据库链接:

    HGNC: 9797

    OMIM: 603417

    KEGG: hsa:5877

    STRING: 9606.ENSP00000356231

    UniGene: Hs.90875