RAB4B Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RAB4B Polyclonal antibody
Uniprot No.：

P61018
基因名：

RAB4B
别名：

1500031G17Rik antibody; FLJ78649 antibody; MGC52123 antibody; OTTMUSP00000026157 antibody; RAB4B antibody; RAB4B; member RAS oncogene family antibody; RAB4B_HUMAN antibody; Ras related GTP binding protein 4b antibody; Ras related protein Rab 4B antibody; Ras-related protein Rab-4B antibody; Small GTP binding protein RAB4B antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Ras-related protein Rab-4B protein (2-213AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Protein transport. Probably involved in vesicular traffic. Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets.
基因功能参考文献：
1. real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B, the read-through long non-coding RNA (lncRNA), RAB4B, PIM2 and TAOK1 share common binding site of a microRNA, miR-24, in their 3'UTRs PMID: 28306719
2. Interaction between Rab4b and AP1gamma allows the budding of clathrin-coated vesicles for subsequent traffic to recycling endosomes. PMID: 24006255
3. Data conclude that Rab4b is a new important player in the control of GLUT4 trafficking in adipocyte. PMID: 19590752
亚细胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Rab family
数据库链接：

HGNC: 9782

OMIM: 612945

KEGG: hsa:53916

STRING: 9606.ENSP00000469872

UniGene: Hs.631539