QPRT Antibody, Biotin conjugated
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中文名称:QPRT兔多克隆抗体, Biotin偶联
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货号:CSB-PA621868LD01HU
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规格:¥880
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) QPRT Polyclonal antibody
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Uniprot No.:
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基因名:QPRT
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别名:NADC_HUMAN antibody; Nicotinate nucleotide pyrophosphorylase (carboxylating) antibody; Nicotinate-nucleotide pyrophosphorylase [carboxylating] antibody; QAPRTase antibody; QPRT antibody; QPRTase antibody; Quinolinate phosphoribosyltransferase [decarboxylating] antibody; Quinolinate phosphoribosyltransferase antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Nicotinate-nucleotide pyrophosphorylase [carboxylating] protein (113-254AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Biotin
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相关产品
靶点详情
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功能:Involved in the catabolism of quinolinic acid (QA).
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基因功能参考文献:
- Our data suggest that QPRT may play an important role in the pathogenesis of autism spectrum disorders in Chr16p11.2 deletion carriers. PMID: 30443311
- WT1 knock-down gave a corresponding decrease in QPRT gene and protein expression. Chromatin-immunoprecipitation revealed WT1 binding to a conserved site in the first intron of the QPRT gene. PMID: 27889611
- The structural features, size distribution, heat aggregation and ITC studies of the full-length enzyme and the enzyme lacking helix alpha1 strongly suggest that human QPRT acts as a hexamer for cooperative reactant binding via three dimeric subunits and maintaining stability. PMID: 26805589
- Report of the crystal structure of human QPRT bound to its inhibitor phthalic acid (PHT) and kinetic analysis of PHT inhibition of human QPRT. PMID: 24038671
- QPRT is a potential new marker for the immunohistochemical screening of follicular thyroid nodules. PMID: 19321014
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蛋白家族:NadC/ModD family
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