POU3F1 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) POU3F1 Polyclonal antibody
Uniprot No.：

Q03052
基因名：

POU3F1
别名：

class 3 antibody; Oct-6 antibody; OCT6 antibody; Octamer-binding protein 6 antibody; Octamer-binding transcription factor 6 antibody; OTF-6 antibody; OTF6 antibody; PO3F1_HUMAN antibody; POU class 3 homeobox 1 antibody; POU domain antibody; POU domain class 3 transcription factor 1 antibody; POU domain transcription factor SCIP antibody; pou3f1 antibody; SCIP antibody; transcription factor 1 antibody
宿主：

Rabbit
反应种属：

Human, Mouse, Rat
免疫原：

Recombinant Human POU domain, class 3, transcription factor 1 protein (59-257AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，POU3F1 Antibody (CSB-PA018396LA01HU)，的标记方式是Non-conjugated。对于POU3F1 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA018396LB01HU	POU3F1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA018396LC01HU	POU3F1 Antibody, FITC conjugated
Biotin	CSB-PA018396LD01HU	POU3F1 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB, IHC
推荐稀释比：

Application Recommended Dilution

WB 1:500-1:5000

IHC 1:20-1:200
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes.
基因功能参考文献：
1. Combined high OATP1A2/high OCT6 may be a potential predictor of response to anthracycline/taxane-based chemotherapy in breast cancer PMID: 24671357
2. CpG island hypermethylation contributes to down-regulation of Oct-6 mRNA expression in hepatocellular carcinoma. PMID: 21448695
3. Our results suggest that Tst-1 and Skn-1a regulate expression of MMPs in keratinocytes and effect both the expression and activation of these proteolytic enzymes. PMID: 17195013
4. Strict control of Pou3f1 transgene expression is critical to proper myelination, and factors responsible for Pouf31 downregulation during myelination may play important roles in the development of peripheral neuropathies. PMID: 17959798
亚细胞定位：

Nucleus.
蛋白家族：

POU transcription factor family, Class-3 subfamily
组织特异性：

Expressed in embryonal stem cells and in the developing brain.
数据库链接：

HGNC: 9214

OMIM: 602479

KEGG: hsa:5453

STRING: 9606.ENSP00000362103

UniGene: Hs.1837

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200