PKD1L2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) PKD1L2 Polyclonal antibody
Uniprot No.：

Q7Z442
基因名：

PKD1L2
别名：

PKD1L2 antibody; KIAA1879 antibody; PC1L2 antibody; Polycystic kidney disease protein 1-like 2 antibody; PC1-like 2 protein antibody; Polycystin-1L2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
基因功能参考文献：
1. Study found an association between a 6.2 kb dele- tion in the PKD1L2 gene and colorectal cancer in a Korean population. PMID: 27605020
2. genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129
3. PKD1L2 is expressed in the developing and adult heart and kidney. PMID: 15203210
4. Ectopic expression of PKD1L2 in transgenic mice caused severe muscle atrophy. PMID: 19578180
亚细胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Polycystin family
组织特异性：

Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
数据库链接：

HGNC: 21715

OMIM: 607894

KEGG: hsa:114780

STRING: 9606.ENSP00000469432

UniGene: Hs.413525