PGAP2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) PGAP2 Polyclonal antibody
Uniprot No.：

Q9UHJ9
基因名：

PGAP2
别名：

PGAP2; FRAG1; Post-GPI attachment to proteins factor 2; FGF receptor-activating protein 1
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Post-GPI attachment to proteins factor 2 protein (45-114AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
基因功能参考文献：
1. A Rare Variant in PGAP2 Causes Autosomal Recessive Hyperphosphatasia with Mental Retardation Syndrome, with a Mild Phenotype in Heterozygous Carriers. PMID: 29119105
2. Hypomorphic mutations in PGAP2, encoding a GPI-anchor-remodeling protein, cause autosomal-recessive intellectual disability. PMID: 23561846
3. PGAP2 mutations, affecting the GPI-anchor-synthesis pathway, cause hyperphosphatasia with mental retardation syndrome. PMID: 23561847
相关疾病：

Hyperphosphatasia with mental retardation syndrome 3 (HPMRS3)
亚细胞定位：

Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

PGAP2 family
组织特异性：

Ubiquitously expressed, with highest levels in testis and pancreas.
数据库链接：

HGNC: 17893

OMIM: 614207

KEGG: hsa:27315

STRING: 9606.ENSP00000278243

UniGene: Hs.133968