PEX10 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) PEX10 Polyclonal antibody
Uniprot No.：

O60683
基因名：

PEX10
别名：

AV128229 antibody; Gm142 antibody; MGC1998 antibody; NALD antibody; OTTHUMP00000001658 antibody; PBD6A antibody; PBD6B antibody; peroxin 10 antibody; Peroxin-10 antibody; Peroxisomal biogenesis factor 10 antibody; Peroxisome assembly protein 10 antibody; Peroxisome biogenesis factor 10 antibody; PEX10 antibody; PEX10_HUMAN antibody; RING finger protein 69 antibody; RNF69 antibody; RP23-298E4.1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Peroxisome biogenesis factor 10 protein (63-157AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Somewhat implicated in the biogenesis of peroxisomes.
基因功能参考文献：
1. This study demonstrated that two mutations in PEX10 were found in the three peroxisomal biogenesis disorders patients: c.827G>T (novel) causing the missense change p.Cys276Phe and c.932G>A causing the missense change p.Arg311Gln. PMID: 27230853
2. abnormal expression of PEX10 gene resulting from copy number variations of 1p36 region may be associated with the epilepsy phenotype PMID: 25636090
3. child and an adult of normal intelligence with progressive ataxia, axonal motor neuropathy, decreased vibration sense and cerebellar atrophy; 2 mutations in PEX10 found in child, c.992G>A and c.764_765insA, and in the adult, c.2T>C and c.790C>T PMID: 20695019
4. Genetic heterogeneity in Japanese patients with peroxisome biogenesis disorders and evidence for a founder haplotype for the most common mutation in PEX10 gene. PMID: 14713216
5. the relative fraction of disease-causing alleles that occur in the coding and splice junction sequences of PEX10 gene. PMID: 19105186
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相关疾病：

Peroxisome biogenesis disorder complementation group 7 (PBD-CG7); Peroxisome biogenesis disorder 6A (PBD6A); Peroxisome biogenesis disorder 6B (PBD6B)
亚细胞定位：

Peroxisome membrane; Peripheral membrane protein.
蛋白家族：

Pex2/pex10/pex12 family
数据库链接：

HGNC: 8851

OMIM: 602859

KEGG: hsa:5192

UniGene: Hs.732228