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PCDH20 Antibody, FITC conjugated

  • 中文名称:
    PCDH20兔多克隆抗体, FITC偶联
  • 货号:
    CSB-PA822719LC01HU
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) PCDH20 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PCDH20
  • 别名:
    FLJ22218 antibody; PCD20_HUMAN antibody; PCDH 13 antibody; PCDH 20 antibody; PCDH13 antibody; PCDH20 antibody; Protocadherin 13 antibody; Protocadherin 20 antibody; Protocadherin-13 antibody; Protocadherin-20 antibody; Protocadherin13 antibody; Protocadherin20 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Protocadherin-20 protein (61-360AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    FITC
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Potential calcium-dependent cell-adhesion protein.
  • 基因功能参考文献:
    1. low expression of PCDH20 was found to be associated with poor OS in HCC patients; hence, this protein represents a promising potential prognostic biomarker PMID: 27935871
    2. Study shows that PCDH20 expression is downregulated in nasopharyngeal carcinoma cells (NPC) and identified it as a functional tumor suppressor and an important antagonist of Wnt/beta-catenin signaling and EMT, with frequent epigenetic inactivation in NPC. PMID: 25736877
    3. In conclusion, these data here strongly suggested that PCDH20 may act as a candidate tumour suppressor in hepatocellular carcinoma. PMID: 24910204
  • 亚细胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 数据库链接:

    HGNC: 14257

    OMIM: 614449

    KEGG: hsa:64881

    STRING: 9606.ENSP00000386653

    UniGene: Hs.391781