PARD6G Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) PARD6G Polyclonal antibody
Uniprot No.：

Q9BYG4
基因名：

PARD6G
别名：

PARD6G antibody; PAR6G antibody; Partitioning defective 6 homolog gamma antibody; PAR-6 gamma antibody; PAR6D antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Partitioning defective 6 homolog gamma protein (249-326AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
基因功能参考文献：
1. This paper shows Par6G as a negative regulator of the phosphatidylinositol 3'-kinase/phosphoinositide-dependent protein kinase 1/Akt pathway and epithelial cell proliferation and evidence for frequent inactivation of Par6G gene in epithelial cancers. PMID: 26073086
2. this study is the first to identify Par6gamma as a component of the mother centriole and to report a role of a mother centriole protein in the regulation of centrosomal protein composition. PMID: 23264737
亚细胞定位：

Cytoplasm. Cell membrane. Cell junction, tight junction.
蛋白家族：

PAR6 family
组织特异性：

Widely expressed, with a higher expression in fetal and adult kidney.
数据库链接：

HGNC: 16076

OMIM: 608976

KEGG: hsa:84552

STRING: 9606.ENSP00000343144

UniGene: Hs.654920