NUP155 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NUP155 Polyclonal antibody
Uniprot No.：

O75694
基因名：

NUP155
别名：

155 kDa nucleoporin antibody; ATFB15 antibody; D930027M19Rik antibody; KIAA0791 antibody; mKIAA0791 antibody; N155 antibody; NU155_HUMAN antibody; Nuclear pore complex protein Nup155 antibody; nucleoporin 155kD antibody; Nucleoporin Nup155 antibody; Nup155 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Nuclear pore complex protein Nup155 protein (1102-1391AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产品提供形式：

Liquid
应用范围：

ELISA, WB
推荐稀释比：

Application Recommended Dilution

WB 1:1000-1:5000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Essential component of nuclear pore complex. Could be essessential for embryogenesis. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.
基因功能参考文献：
1. The Nup155-mediated localization was required for HDAC4's effect on gene expression. PMID: 21464227
2. The Nup155 depletion massively alters nuclear envelope structure, causing a dramatic decrease in Nuclear pore complexes numbers and the improper targeting of membrane proteins to the inner nuclear membrane. PMID: 20974814
3. These human and mouse studies indicate that loss of NUP155 function causes atrial fibrillation by altering mRNA and protein transport and link the nuclear pore complex to cardiovascular disease. PMID: 19070573
相关疾病：

Atrial fibrillation, familial, 15 (ATFB15)
亚细胞定位：

Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
蛋白家族：

Non-repetitive/WGA-negative nucleoporin family
组织特异性：

Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
数据库链接：

HGNC: 8063

OMIM: 606694

KEGG: hsa:9631

STRING: 9606.ENSP00000231498

UniGene: Hs.547696