NUDT11 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NUDT11 Polyclonal antibody
Uniprot No.：

Q96G61
基因名：

NUDT11
别名：

NUDT11 antibody; APS1 antibody; DIPP3BDiphosphoinositol polyphosphate phosphohydrolase 3-beta antibody; DIPP-3-beta antibody; DIPP3-beta antibody; hDIPP3beta antibody; EC 3.6.1.52 antibody; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta antibody; Diadenosine hexaphosphate hydrolase antibody; AMP-forming) antibody; EC 3.6.1.60 antibody; Nucleoside diphosphate-linked moiety X motif 11 antibody; Nudix motif 11 antibody; hAps1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein (1-164AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
基因功能参考文献：
1. NUDT11, HNF1B, and SLC22A3 genes have roles in prostate cancer pathogenesis PMID: 22730461
2. The NUDT11 gene, located on chromosome X, is preferentially expressed in the testis PMID: 12105228
3. Cloning and characterisation of NUDT11 as a diadenosine polyphosphate-metabolising Nudix hydrolase. PMID: 12121577
亚细胞定位：

Cytoplasm.
蛋白家族：

Nudix hydrolase family, DIPP subfamily
组织特异性：

Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart.
数据库链接：

HGNC: 18011

OMIM: 300528

KEGG: hsa:55190

STRING: 9606.ENSP00000365160

UniGene: Hs.200016