NR2C2AP Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NR2C2AP Polyclonal antibody
Uniprot No.：

Q86WQ0
基因名：

NR2C2AP
别名：

nr2c2ap antibody; NR2CA_HUMAN antibody; Nuclear receptor 2C2 associated protein antibody; Nuclear receptor 2C2-associated protein antibody; Repressor for TR4 transactivation antibody; TR4 orphan receptor associated 16 kDa protein antibody; TR4 orphan receptor associated protein TRA16 antibody; TR4 orphan receptor-associated 16 kDa protein antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Nuclear receptor 2C2-associated protein (7-139AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
基因功能参考文献：
1. High TRA16 expression promotes small cell lung carcinoma by activating estrogen receptor beta and blocking testicular orphan nuclear receptor 2 PMID: 23129017
2. TRA16 may function as a novel repressor to selectively suppress the TR4-mediated transactivation PMID: 12486131
3. Together, these findings provide the first in vivo evidence that an orphan nuclear receptor, such as TR4, may play major roles in the RA-mediated apoptosis or differentiation in P19 cells. PMID: 15381082
4. Taken together, these results suggested that TR4 should be one of important regulators of OXT gene expression. PMID: 17054912
亚细胞定位：

Nucleus.
蛋白家族：

NR2C2AP family
组织特异性：

Expressed in all tissues examined, with highest expression in heart, skeletal muscle and pancreas.
数据库链接：

HGNC: 30763

OMIM: 608719

KEGG: hsa:126382

STRING: 9606.ENSP00000332823

UniGene: Hs.708153