NKX2-8 Antibody, HRP conjugated
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中文名称:NKX2-8兔多克隆抗体, HRP偶联
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货号:CSB-PA015847LB01HU
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规格:¥880
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) NKX2-8 Polyclonal antibody
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Uniprot No.:
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基因名:NKX2-8
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别名:Homeobox protein NK 2 homolog H antibody; Homeobox protein NK-2 homolog H antibody; Homeobox protein Nkx 2.8 antibody; Homeobox protein Nkx-2.8 antibody; NK 2 homolog 8 antibody; NK 2 homolog H antibody; NK2 homeobox 8 antibody; NK2 transcription factor related; locus 8 antibody; Nkx2 9 antibody; Nkx2-8 antibody; NKX2.8 antibody; NKX28_HUMAN antibody; NKX2G antibody; NKX2H antibody; OTTHUMP00000027959 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Homeobox protein Nkx-2.8 protein (1-160AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:HRP
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相关产品
靶点详情
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基因功能参考文献:
- Results show that Nkx2-8 functions as a tumor suppressor in esophageal squamous cell carcinoma (ESCC), the downregulation of which contributes to NF-kappaB P65 activation and ESCC angiogenesis. PMID: 23604637
- overexpression of Nkx2.8 resulted in downregulation of p-FOXO3a and inhibition of MEK/ERK pathway activity. silencing Nkx2.8 led to upregulation of p-FOXO3a and increase of MEK/ERK pathway activity. PMID: 22223847
- Most tumors have low expression of Nkx2-8, and its expression can inhibit growth of some lung cancer cells. PMID: 21148747
- A murine Nkx2.8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor. PMID: 12167706
- Coactivation of the TTF-1 and NKX2-8 pathways identified a cluster of lung cancer patients with poor survival and were shown to exhibit resistance to cisplatin PMID: 19279207
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亚细胞定位:Nucleus.
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蛋白家族:NK-2 homeobox family
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数据库链接:
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