NEUROG2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NEUROG2 Polyclonal antibody
Uniprot No.：

Q9H2A3
基因名：

NEUROG2
别名：

Atoh 4 antibody; Atoh4 antibody; bHLHa8 antibody; Class A basic helix-loop-helix protein 8 antibody; Math 4A antibody; Math4A antibody; MGC antibody; MGC46562 antibody; NEUROG 2 antibody; NEUROG2 antibody; Neurogenin-2 antibody; Neurogenin2 antibody; NGN 2 antibody; NGN-2 antibody; NGN2 antibody; NGN2_HUMAN antibody; Protein atonal homolog 4 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Neurogenin-2 protein (194-262AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
基因功能参考文献：
1. Study shows neurogenin 2 enhances the generation of patient-specific induced neuronal cells. PMID: 25912433
2. Results show that neurogenin-1 and -2 drive homogeneous differentiation of human stem cells into bipolar neurons in 4 days in defined media. PMID: 25403753
3. human embryonic progenitors expressing neurogenin-2 stimulate axonal sprouting and improve motor recovery after severe spinal cord injury PMID: 21209909
4. Novel compound heterozygous variants (Gly56Arg and Asp206Glu) were found in a 91-year normal male, suggesting that mutations in the coding region of the NEUROG2 gene play little or no role in the development of PD. PMID: 19879328
5. expression of Ngn2 during the differentiation of neuronl human embryo stem cells. PMID: 17784840
6. Rat and mouse species-dependent differences of Nurr1 and Ngn2 actions in dopamine neuron differentiation. PMID: 18242186
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亚细胞定位：

Nucleus.
数据库链接：

HGNC: 13805

OMIM: 606624

KEGG: hsa:63973

STRING: 9606.ENSP00000317333

UniGene: Hs.744415