NETO1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NETO1 Polyclonal antibody
Uniprot No.：

Q8TDF5
基因名：

NETO1
别名：

AI851453 antibody; BCTL1 antibody; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody; BTCL1 antibody; C130005O10Rik antibody; FLJ41325 antibody; Neto1 antibody; NETO1_HUMAN antibody; Neuropilin and tolloid like 1 antibody; Neuropilin and tolloid-like protein 1 antibody; RGD1566269 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Neuropilin and tolloid-like protein 1 protein (367-507AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
基因功能参考文献：
1. Neto1 is concluded to be a component of amyloid precursor protein /NMDA receptor trafficking complexes PMID: 23621516
2. no evidence for the association of NETO1 with schizophrenia in the Japanese population PMID: 22205981
3. Mouse neto1 plays a critical role in spatial learning and memory through the regulation of NMDAR subunit abundance at synapses. PMID: 19243221
亚细胞定位：

[Isoform 2]: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 1]: Secreted.
组织特异性：

Isoform 1 and isoform 2 are retina-specific. Isoform 3 is found in retina as well as at lower levels in adult and fetal brain.
数据库链接：

HGNC: 13823

OMIM: 607973

KEGG: hsa:81832

STRING: 9606.ENSP00000313088

UniGene: Hs.465407