NDUFB6 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NDUFB6 Polyclonal antibody
Uniprot No.：

O95139
基因名：

NDUFB6
别名：

NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; Complex I-B17; CI-B17; NADH-ubiquinone oxidoreductase B17 subunit
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 protein (2-67AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
基因功能参考文献：
1. we propose that NDUFB6 is a possible tumor suppressor of metastatic ccRCCs. PMID: 25315157
2. NDUFS6 has a Zn-binding site and is essential for biogenesis of mitochondrial complex I PMID: 25902503
3. NDUFB6 subunit is required for complex I activity. PMID: 21964293
4. Results demonstrate that genetic, epigenetic, and nongenetic factors associate with NDUFB6 expression in human muscle and suggest that genetic and epigenetic factors may interact to increase age-dependent susceptibility to insulin resistance. PMID: 17948130
5. Polymorphism in the NDUFB6 gene from respiratory chain complex I related to ATP synthesis and insulin sensitivity response to exercise training found in relatives of humans with type 2 diabetes. PMID: 19265027
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亚细胞定位：

Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
蛋白家族：

Complex I NDUFB6 subunit family
数据库链接：

HGNC: 7701

OMIM: 603322

KEGG: hsa:4712

STRING: 9606.ENSP00000369176

UniGene: Hs.493668