NCAM2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) NCAM2 Polyclonal antibody
Uniprot No.：

O15394
基因名：

NCAM2
别名：

Cell adhesion molecule, neural, 2 antibody; MGC51008 antibody; N CAM 2 antibody; N CAM 21 antibody; N CAM2 antibody; N CAM21 antibody; N-CAM-2 antibody; NCAM 2 antibody; NCAM 21 antibody; NCAM-2 antibody; Ncam2 antibody; NCAM2_HUMAN antibody; NCAM21 antibody; Neural cell adhesion molecule 2 antibody; OCAM GPI antibody; R4B12 antibody; RB 8 neural cell adhesion molecule antibody; RB8 neural cell adhesion molecule antibody; RNCAM antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Neural cell adhesion molecule 2 protein (209-333AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
基因功能参考文献：
1. Our reported case raises the questions whether the NCAM2-deletion is the true cause of the autism spectrum disorder or only a risk factor and whether there might be any connection in NCAM2 with skull-size PMID: 27596683
2. Abeta-dependent disruption of NCAM2 functions in Alzheimer's disease hippocampus contributes to synapse loss. PMID: 26611261
3. A complete structural model of the entire ectodomain of human NCAM2 has been assembled from crystal structures of six recombinant proteins corresponding to different regions of the ectodomain. PMID: 21300289
4. High NCAM2 is associated with increased 5-Fluorouracil sensitivity in prostate and breast cancer. PMID: 21214674
5. In the crystal structure, two Ig domains interact by domain swapping, as the two N-terminal beta-strands are interchanged. PMID: 18706912
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亚细胞定位：

Cell membrane; Single-pass type I membrane protein.
组织特异性：

Expressed most strongly in adult and fetal brain.
数据库链接：

HGNC: 7657

OMIM: 602040

KEGG: hsa:4685

STRING: 9606.ENSP00000383392

UniGene: Hs.473450