MTERF4 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MTERF4 Polyclonal antibody
Uniprot No.：

Q7Z6M4
基因名：

MTERF4
别名：

FLJ16261 antibody; HSPC096 antibody; MGC61716 antibody; MTER2_HUMAN antibody; MTERF domain containing 2 antibody; mTERF domain-containing protein 2 antibody; Mterfd2 antibody; OTTHUMP00000200479 antibody; OTTHUMP00000200519 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Transcription termination factor 4, mitochondrial protein (45-87AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S).
基因功能参考文献：
1. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease. PMID: 27894840
2. analysis of the 3D crystal structure of the human MTERF4-NSUN4 complex PMID: 22949673
亚细胞定位：

Mitochondrion.
蛋白家族：

MTERF family
数据库链接：

HGNC: 28785

OMIM: 615393

KEGG: hsa:130916

STRING: 9606.ENSP00000241527

UniGene: Hs.159556