MSC Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MSC Polyclonal antibody
Uniprot No.：

O60682
基因名：

MSC
别名：

ABF-1 antibody; ABF1 antibody; Activated B cell factor 1 antibody; Activated B-cell factor 1 antibody; bHLHa22 antibody; Class A basic helix-loop-helix protein 22 antibody; Msc antibody; MUSC_HUMAN antibody; Musculin antibody; MYOR antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Musculin protein (3-143AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.
基因功能参考文献：
1. this study shows that musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity PMID: 28612433
2. results demonstrate that ABF-1 facilitates formation of memory B cells but prevents plasma cell differentiation. PMID: 25070843
3. role in repressing lymphotoxin alpha PMID: 15052269
4. ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. PMID: 18368067
亚细胞定位：

Nucleus.
组织特异性：

Expressed in lymphoid tissues, B-cell lines and activated B-cells.
数据库链接：

HGNC: 7321

OMIM: 603628

KEGG: hsa:9242

STRING: 9606.ENSP00000321445

UniGene: Hs.442619