MRPS27 Antibody

中文名称：

MRPS27兔多克隆抗体
货号：

CSB-PA022313
规格：

￥2024
图片：
Western blot analysis of extracts from HeLa cells and HUVEC cells, using MRPS27 antibody.
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MRPS27 Polyclonal antibody
Uniprot No.：

Q92552
基因名：

MRPS27
宿主：

Rabbit
反应种属：

Human,Mouse
免疫原：

Synthesized peptide derived from internal of Human MRPS27.
免疫原种属：

Homo sapiens (Human)
克隆类型：

Polyclonal
纯化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度：

It differs from different batches. Please contact us to confirm it.
产品提供形式：

Liquid
应用范围：

ELISA,WB
推荐稀释比：

Application Recommended Dilution

WB 1:500-1:3000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth.
基因功能参考文献：
1. we verified for the first time that mitochondrial ribosomal protein S23 expression was upregulated in hepatocellular carcinoma. High mitochondrial ribosomal protein S23 levels can predict poor clinical outcomes in hepatocellular carcinoma, and this protein plays a key role in tumor proliferation. Therefore, mitochondrial ribosomal protein S23 may be a potential therapeutic target for hepatocellular carcinoma. PMID: 28714366
2. MRPS27 is required for mitochondrial protein synthesis PMID: 22841715
亚细胞定位：

Cytoplasm. Mitochondrion.
蛋白家族：

Mitochondrion-specific ribosomal protein mS27 family
组织特异性：

Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level). Ubiquitous.
数据库链接：

HGNC: 14512

OMIM: 611989

KEGG: hsa:23107

STRING: 9606.ENSP00000261413

UniGene: Hs.482491