MPI Antibody

中文名称：

MPI兔多克隆抗体
货号：

CSB-PA014754LA01HU
规格：

￥440
图片：
Immunofluorescent analysis of HepG2 cells using CSB-PA014754LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MPI Polyclonal antibody
Uniprot No.：

P34949
基因名：

MPI
别名：

ody; CDG1B antibody; FLJ39201 antibody; Mannose 6 phosphate isomerase antibody; Mannose-6-phosphate isomerase antibody; MANNOSEPHOSPHATE ISOMERASE antibody; MGC94106 antibody; MPI antibody; MPI_HUMAN antibody; Phosphohexomutase antibody; phosphomannose isomerase 1 antibody; Phosphomannose isomerase antibody; PMI antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Mannose-6-phosphate isomerase protein (213-350AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，MPI Antibody (CSB-PA014754LA01HU)，的标记方式是Non-conjugated。对于MPI Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA014754LB01HU	MPI Antibody, HRP conjugated	ELISA
FITC	CSB-PA014754LC01HU	MPI Antibody, FITC conjugated
Biotin	CSB-PA014754LD01HU	MPI Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IF
推荐稀释比：

Application Recommended Dilution

IF 1:50-1:200
Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
基因功能参考文献：
1. This work provides mechanistic evidence by which mannose phosphate isomerase loss induces p53, and identifies mannose phosphate isomerase as a novel regulator of p53 and Warburg metabolism. PMID: 28644127
2. Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts PMID: 21949237
3. The mannose-6-phosphate-enzyme complex is developed and the key residues involved in the ligand binding are determined. Our results suggest a hydride transfer mechanism of alpha-hydrogen between the C1 and C2 positions. PMID: 16488169
相关疾病：

Congenital disorder of glycosylation 1B (CDG1B)
亚细胞定位：

Cytoplasm.
蛋白家族：

Mannose-6-phosphate isomerase type 1 family
组织特异性：

Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
数据库链接：

HGNC: 7216

OMIM: 154550

KEGG: hsa:4351

STRING: 9606.ENSP00000318318

UniGene: Hs.75694