MILR1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MILR1 Polyclonal antibody
Uniprot No.：

Q7Z6M3
基因名：

MILR1
别名：

Allergin-1 antibody; Allergy inhibitory receptor 1 antibody; C17orf60 antibody; Mast cell antigen 32 antibody; Mast cell immunoglobulin-like receptor 1 antibody; MCA-32 antibody; MCA32 antibody; MILR1 antibody; MILR1_HUMAN antibody; Probable mast cell antigen 32 homolog antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Allergin-1 protein (249-343AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
基因功能参考文献：
1. Data indicate that the rs6504230 polymorphism affects MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) expression levels, leading to a susceptibility to producing specific IgE antibodies against common allergens. PMID: 25007884
2. Allergin-1S1, a splicing isoform of Allergin-1, is predominantly expressed on human primary MC in both bronchoalveolar lavage fluid and nasal scratching specimens. Moreover, Allergin-1S1 inhibits IgE-mediated activation from human primary MC in BAL fluid. PMID: 24116093
3. It is a immunoglobulin-like receptor which regulates the activation of mast cell.(review) PMID: 24552759
亚细胞定位：

Cell membrane; Single-pass type I membrane protein.
组织特异性：

Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level).
数据库链接：

HGNC: 27570

KEGG: hsa:284021

UniGene: Hs.631749