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  4. MGAT4B Antibody, FITC conjugated

MGAT4B Antibody, FITC conjugated

说明书
  • 中文名称：
    MGAT4B兔多克隆抗体, FITC偶联
  • 货号：
    CSB-PA890781LC01HU
  • 规格：
    ￥880
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) MGAT4B Polyclonal antibody
  • Uniprot No.：
    Q9UQ53
  • 基因名：
    MGAT4B
  • 别名：
    3-D-mannoside beta-1 antibody; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B antibody; 4-N-acetylglucosaminyltransferase IVb antibody; Alpha 1 3 mannosyl glycoprotein beta 1 4 N acetylglucosaminyltransferase antibody; Alpha-1 antibody; Aminyltransferase antibody; GlcNAc T IVb antibody; GlcNAc-T IVb antibody; GNT IV antibody; GNT IVB antibody; GnT-IVb antibody; GNTIV antibody; GNTIVB antibody; Mannosyl (alpha 1 3) glycoprotein beta 1 4 N acetylglucosaminyltransferase isozyme B antibody; MGAT 4B antibody; mgat4b antibody; MGT4B_HUMAN antibody; N acetylglucosaminyltransferase IVb antibody; N glycosyl oligosaccharide glycoprotein antibody; N glycosyl oligosaccharide glycoprotein N acetylglucosaminyltransferase IVb antibody; N-acetylglucosaminyltransferase IVb antibody; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb antibody; UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IV antibody; UDP N acetylglucosamine alpha 1 3 D mannoside beta 1 4 N acetylglucosaminyltransferase IVb antibody; UDP-N-acetylglucosamine: alpha-1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B protein (380-522AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    FITC
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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MGAT4B antibodies

MGAT4B Proteins

靶点详情

  • 功能：
    Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
  • 基因功能参考文献：
    1. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats). PMID: 25944901
    2. analysis of expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer PMID: 16434023
    3. GnT-IVa is more active than GnT-IVb under physiological conditions and it primarily contributes to the biosynthesis of N-glycans. PMID: 17006639
    4. We investigated mRNA levels of glycosyltransferases, namely, N-acetylglucosaminyltransferase a (GnT)-IVb, and found that (GnT)-IVb expression was increased in HLE-cells Epirubicin resistant. PMID: 17488527
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 54 family
  • 组织特异性：
    Widely expressed. Strongly overexpressed in pancreatic cancer.
  • 数据库链接：

    HGNC: 7048

    OMIM: 604561

    KEGG: hsa:11282

    STRING: 9606.ENSP00000338487

    UniGene: Hs.567419

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