METAP1 Antibody, FITC conjugated
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中文名称:METAP1兔多克隆抗体, FITC偶联
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货号:CSB-PA013715LC01HU
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规格:¥880
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) METAP1 Polyclonal antibody
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Uniprot No.:
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基因名:METAP1
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别名:AMPM1_HUMAN antibody; DKFZp781C0419 antibody; KIAA0094 antibody; MAP 1 antibody; MAP1A antibody; MetAP 1 antibody; metap1 antibody; MetAP1A antibody; Methionine aminopeptidase 1 antibody; Peptidase M 1 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Methionine aminopeptidase 1 protein (54-125AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:FITC
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶点详情
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功能:Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.
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基因功能参考文献:
- Data indicate that pyridinylpyrimidine-based molecules displayed species specificity behavior against methionine aminopeptidases (MetAPs). PMID: 23767698
- Data show that human methionine aminopeptidase 1 (MetAP1) fully rescued the slow growth phenotype associated with deletion of yeast MetAP1, suggesting that the yeast and human proteins may have similar roles in vivo. PMID: 12144506
- results suggest that MetAP1 plays an important role in G(2)/M phase of the cell cycle and that it may serve as a promising target for the discovery and development of new anticancer agents PMID: 17114291
- Human MetAP1 is distinct from other members of the MetAP superfamily in the number of metal ions employed and likely mechanism of catalysis. PMID: 17929833
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亚细胞定位:Cytoplasm.
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蛋白家族:Peptidase M24A family, Methionine aminopeptidase type 1 subfamily
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数据库链接:
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