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METAP1 Antibody, FITC conjugated

  • 中文名称:
    METAP1兔多克隆抗体, FITC偶联
  • 货号:
    CSB-PA013715LC01HU
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) METAP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    METAP1
  • 别名:
    AMPM1_HUMAN antibody; DKFZp781C0419 antibody; KIAA0094 antibody; MAP 1 antibody; MAP1A antibody; MetAP 1 antibody; metap1 antibody; MetAP1A antibody; Methionine aminopeptidase 1 antibody; Peptidase M 1 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Methionine aminopeptidase 1 protein (54-125AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    FITC
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.
  • 基因功能参考文献:
    1. Data indicate that pyridinylpyrimidine-based molecules displayed species specificity behavior against methionine aminopeptidases (MetAPs). PMID: 23767698
    2. Data show that human methionine aminopeptidase 1 (MetAP1) fully rescued the slow growth phenotype associated with deletion of yeast MetAP1, suggesting that the yeast and human proteins may have similar roles in vivo. PMID: 12144506
    3. results suggest that MetAP1 plays an important role in G(2)/M phase of the cell cycle and that it may serve as a promising target for the discovery and development of new anticancer agents PMID: 17114291
    4. Human MetAP1 is distinct from other members of the MetAP superfamily in the number of metal ions employed and likely mechanism of catalysis. PMID: 17929833
  • 亚细胞定位:
    Cytoplasm.
  • 蛋白家族:
    Peptidase M24A family, Methionine aminopeptidase type 1 subfamily
  • 数据库链接:

    HGNC: 15789

    OMIM: 610151

    KEGG: hsa:23173

    STRING: 9606.ENSP00000296411

    UniGene: Hs.480364