MEIKIN Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MEIKIN Polyclonal antibody
Uniprot No.：

A0A087WXM9
基因名：

MEIKIN
别名：

MEIKINMeiosis-specific kinetochore protein antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Meiosis-specific kinetochore protein (18-91AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.
基因功能参考文献：
1. Single marker analysis indicated that SNP5 (rs1355095) in LOC728637 is associated with schizophrenia in Han Chinese. PMID: 18718982
亚细胞定位：

Chromosome, centromere. Chromosome, centromere, kinetochore.
数据库链接：

HGNC: 51253

OMIM: 616223

KEGG: hsa:728637

UniGene: Hs.631802