MED30 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MED30 Polyclonal antibody
Uniprot No.：

Q96HR3
基因名：

MED30
别名：

MED30 antibody; MED30_HUMAN antibody; Mediator complex subunit 30 antibody; Mediator of RNA polymerase II transcription subunit 30 antibody; THRAP6 antibody; Thyroid hormone receptor-associated protein 6 antibody; Thyroid hormone receptor-associated protein complex 25 kDa component antibody; TRAP/Mediator complex component TRAP25 antibody; Trap25 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Mediator of RNA polymerase II transcription subunit 30 protein (67-165AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
基因功能参考文献：
1. MED30 seems to be involved in the progression of the renal cell carcinoma (RCC). PMID: 29661722
2. Knockdown of MED30 led to reduction of the tumour parameters proliferation, migration, and invasion in the bladder cancer (BCa) cell lines. PMID: 29187445
3. analysis of a novel transcript of MED30, termed MED30 short (MED30s) generated by alternative splicing PMID: 20493979
4. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. PMID: 11909976
亚细胞定位：

Nucleus.
蛋白家族：

Mediator complex subunit 30 family
组织特异性：

Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
数据库链接：

HGNC: 23032

OMIM: 610237

KEGG: hsa:90390

STRING: 9606.ENSP00000297347

UniGene: Hs.492612