MED22 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MED22 Polyclonal antibody
Uniprot No.：

Q15528
基因名：

MED22
别名：

MED22 antibody; SURF5Mediator of RNA polymerase II transcription subunit 22 antibody; Mediator complex subunit 22 antibody; Surfeit locus protein 5 antibody; Surf-5 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Mediator of RNA polymerase II transcription subunit 22 protein (2-140AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
基因功能参考文献：
1. functional communications between the MED1 subunit and the MED24-containing submodule that mediate estrogen receptor functions and growth of both normal mammary epithelial cells and breast carcinoma cells. PMID: 22331469
2. Hu-Surf5 encodes three different transcripts, Surf-5a, Surf-5b, and Surf-5c, which result from alternative splicing. PMID: 11891058
3. This publication also contains human sequence. PMID: 8586415
亚细胞定位：

Nucleus.
蛋白家族：

Mediator complex subunit 22 family
数据库链接：

HGNC: 11477

OMIM: 185641

KEGG: hsa:6837

STRING: 9606.ENSP00000342343

UniGene: Hs.78354