MCUB Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) MCUB Polyclonal antibody
Uniprot No.：

Q9NWR8
基因名：

MCUB
别名：

MCUB; CCDC109B; Calcium uniporter regulatory subunit MCUb, mitochondrial; MCUb; Coiled-coil domain-containing protein 109B
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
基因功能参考文献：
1. This study elucidated a role for CCDC109B as an oncogene and a prognostic marker in human gliomas. PMID: 28754121
2. MCUb (also known as CCDC109b) is a paralogue of MCU (CCDC109a). MCUb physically resides within the mitochondrial uniporter complex (uniplex), which consists of the MCU, MCUb, EMRE, MICU1, and MICU2. PMID: 24231807
亚细胞定位：

Mitochondrion inner membrane; Multi-pass membrane protein.
蛋白家族：

MCU (TC 1.A.77) family
数据库链接：

HGNC: 26076

KEGG: hsa:55013

STRING: 9606.ENSP00000378145

UniGene: Hs.234149