MAGEA2 Antibody

中文名称：

MAGEA2兔多克隆抗体
货号：

CSB-PA187447
规格：

￥1100
图片：
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human leiomyosarcoma tissue, Primary antibody: CSB-PA187447(MAGEA2 Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
其他：

产品详情

Uniprot No.：

P43356
基因名：

MAGEA2
别名：

MAGEA2 antibody; MAGE2 antibody; MAGEA2A; antibody; MAGEA2B antibody; MAGE2 antibody; MAGEA2 antibody; Melanoma-associated antigen 2 antibody; Cancer/testis antigen 1.2 antibody; CT1.2 antibody; MAGE-2 antigen antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Synthetic peptide of Human MAGEA2
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
抗体亚型：

IgG
纯化方式：

Antigen affinity purification
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
产品提供形式：

Liquid
应用范围：

ELISA,WB
推荐稀释比：

Application Recommended Dilution

ELISA 1:1000-1:5000

WB 1:200-1:1000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Negatively regulates acetylation and sumoylation of PML and represses PML-induced p53/TP53 acetylation and activation.
亚细胞定位：

Nucleus. Nucleus, PML body.
组织特异性：

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
数据库链接：

HGNC: 6800

OMIM: 300173

KEGG: hsa:266740

STRING: 9606.ENSP00000359307

UniGene: Hs.534597

Application	Recommended Dilution
ELISA	1:1000-1:5000
WB	1:200-1:1000