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  4. LRIG2 Antibody, Biotin conjugated

LRIG2 Antibody, Biotin conjugated

说明书
  • 中文名称：
    LRIG2兔多克隆抗体, Biotin偶联
  • 货号：
    CSB-PA013085LD01HU
  • 规格：
    ￥880
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) LRIG2 Polyclonal antibody
  • Uniprot No.：
    O94898
  • 基因名：
    LRIG2
  • 别名：
    KIAA0806 antibody; Leucine rich repeats and immunoglobulin like domains 2 antibody; Leucine-rich repeats and immunoglobulin-like domains protein 2 antibody; LIG-2 antibody; LIG2 antibody; LRIG2 antibody; LRIG2_HUMAN antibody; UFS2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Leucine-rich repeats and immunoglobulin-like domains protein 2 protein (833-932AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Biotin
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
    ELISA Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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LRIG2 antibodies

LRIG2 Proteins

靶点详情

  • 基因功能参考文献：
    1. Study demonstrated that LRIG2 promoted the PDGFRBinduced proliferation of glioblastoma multiforme cells in vitro and in vivo through regulating the PDGFRB signalingmediated cell cycle progression. PMID: 30015847
    2. Role of LRIG2 in cancer [review] PMID: 27628597
    3. LRIG2 gene is overexpressed in invasive pituitary adenoma. PMID: 21823015
    4. A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2 PMID: 23313374
    5. Cytoplasmic expression of LRIG2 is associated with meningiomas. PMID: 22484910
    6. LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade. PMID: 21632100
    7. LRIG2 was found to be a glycoprotein with an molecular weight of 132 kDa, which was encoded by a gene on human chromosome 1p13 and its mRNA was present in all tissues analyzed. PMID: 15145052
    8. LRIG proteins may have a role in epidermal homeostasis and psoriasis PMID: 18037903
    9. This is the first report of an LRIG protein showing a negative effect on survival, suggesting that LRIG2 might have a function different from that of LRIG1, and possibly contributing to the etiology of oligodendroglioma. PMID: 18992012

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  • 相关疾病：
    Urofacial syndrome 2 (UFS2)
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm.
  • 组织特异性：
    Detected in all tissues analyzed.
  • 数据库链接：

    HGNC: 20889

    OMIM: 608869

    KEGG: hsa:9860

    STRING: 9606.ENSP00000355396

    UniGene: Hs.448972

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