LRCH1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) LRCH1 Polyclonal antibody
Uniprot No.：

Q9Y2L9
基因名：

LRCH1
别名：

LRCH1 antibody; CHDC1 antibody; KIAA1016 antibody; Leucine-rich repeat and calponin homology domain-containing protein 1 antibody; Calponin homology domain-containing protein 1 antibody; Neuronal protein 81 antibody; NP81 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Leucine-rich repeat and calponin homology domain-containing protein 1 protein (1-105AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
基因功能参考文献：
1. In the analysis of hip osteoarthritis cases with superior maximum joint space narrowing (JSN) versus cases with non-superior maximum JSN we detected association with a variant in the LRCH1 gene. PMID: 27974301
2. Letter: Did not observe an association between LRCH-1 SNPs and knee osteoarthritis. PMID: 22325041
3. A genetic variant in LRCH1 was consistently associated with knee osteoarthritis in 3 samples from 2 populations. PMID: 16447229
4. results suggest that there is no association between LRCH1 and knee osteoarthritis susceptibility PMID: 18049793
亚细胞定位：

Cytoplasm.
数据库链接：

HGNC: 20309

OMIM: 610368

KEGG: hsa:23143

STRING: 9606.ENSP00000374447

UniGene: Hs.507971