LEMD2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) LEMD2 Polyclonal antibody
Uniprot No.：

Q8NC56
基因名：

LEMD2
别名：

LEMD2; LEM domain-containing protein 2; hLEM2
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human LEM domain-containing protein 2 protein (17-204AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope.; Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT. Required for myoblast differentiation involving regulation of ERK signaling.
基因功能参考文献：
1. We conclude that Lem2p/LEM2 is a conserved nuclear site-specific adaptor that recruits Cmp7p/CHMP7 and downstream ESCRT factors to the nuclear envelope. PMID: 28242692
2. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445
相关疾病：

Cataract 46, juvenile-onset (CTRCT46)
亚细胞定位：

Nucleus inner membrane; Multi-pass membrane protein. Note=Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.
组织特异性：

Ubiquitously expressed.
数据库链接：

HGNC: 21244

OMIM: 212500

KEGG: hsa:221496

STRING: 9606.ENSP00000293760

UniGene: Hs.444845