LAMB4 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) LAMB4 Polyclonal antibody
Uniprot No.：

A4D0S4
基因名：

LAMB4
别名：

LAMB4Laminin subunit beta-4 antibody; Laminin beta-1-related protein antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Laminin subunit beta-4 protein (1513-1761AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
基因功能参考文献：
1. We identified a rare single nucleotide variant in the laminin beta 4 gene (LAMB4) that segregated with familial diverticulitis in a dominant pattern and causes a damaging missense substitution (D435N). Targeted sequencing of LAMB4 in 148 non-familial and unrelated sporadic diverticulitis patients identified two additional rare variants in the gene. PMID: 28595269
2. Loss of LAMB4 expression was identified in 17-32% of the GC and CRC. Of note, the loss expression was more common in the cancers with LAMB4 mutation or those with MSI-H. PMID: 25257191
亚细胞定位：

Secreted, extracellular space, extracellular matrix, basement membrane.
数据库链接：

HGNC: 6491

OMIM: 616380

KEGG: hsa:22798

STRING: 9606.ENSP00000205386

UniGene: Hs.62022