KY Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) KY Polyclonal antibody
Uniprot No.：

Q8NBH2
基因名：

KY
别名：

KY antibody; KY_HUMAN antibody; Kyphoscoliosis peptidase antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Kyphoscoliosis peptidase protein (23-170AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC.
基因功能参考文献：
1. This study shown Kyphoscoliosis peptidase (KY) mutation causes a novel congenital myopathy with core targetoid defects in two bother. PMID: 27484770
2. Homozygous KY mutation was identified as a cause of progressive hereditary spastic paraplegia. High KY transcript levels were demonstrated in muscular organs and lower expression in the CNS. PMID: 28488683
3. Homozygous c.1071delG, p.(Thr358Leufs*3) variant of KY causes neuromuscular disorder by introducing a premature stop codon. PMID: 27485408
4. KY expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
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相关疾病：

Myopathy, myofibrillar, 7 (MFM7)
亚细胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
蛋白家族：

Transglutaminase-like superfamily
组织特异性：

Highly expressed in skeletal muscle.
数据库链接：

HGNC: 26576

OMIM: 605739

KEGG: hsa:339855

STRING: 9606.ENSP00000397598

UniGene: Hs.146730