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KLRC3 Antibody, FITC conjugated

  • 中文名称:
    KLRC3兔多克隆抗体, FITC偶联
  • 货号:
    CSB-PA23099C0Rb
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) KLRC3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 别名:
    Killer cell lectin like receptor subfamily C member 3 antibody; KLRC 3 antibody; KLRC3 antibody; NK cell receptor E antibody; NKG2 E activating NK receptor antibody; NKG2 E antibody; NKG2 E type II integral membrane protein antibody; NKG2-E type II integral membrane protein antibody; NKG2-E-activating NK receptor antibody; NKG2E activating NK receptor antibody; NKG2E antibody; NKG2E type II integral membrane protein antibody; NKG2E_HUMAN antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human NKG2-E type II integral membrane protein (94-240AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    FITC
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
  • 基因功能参考文献:
    1. KLRC3 gene expression is linked to glioblastoma aggressiveness. PMID: 27641066
    2. Data indicate that NKG2 receptor NKG2E was capable of associating with CD94 and DAP12 but that the complex was retained intracellularly at the endoplasmic reticulum. PMID: 24935923
    3. Data indicate that the expression of KLRD1 (CD94) and NKG2E (KLRC3) was reduced in NK-enriched cells in fulminant type 1 diabetes. PMID: 24177169
  • 亚细胞定位:
    Membrane; Single-pass type II membrane protein.
  • 组织特异性:
    Natural killer cells.
  • 数据库链接:

    HGNC: 6376

    OMIM: 602892

    KEGG: hsa:3823

    STRING: 9606.ENSP00000437563

    UniGene: Hs.654362