KCNRG Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) KCNRG Polyclonal antibody
Uniprot No.：

Q8N5I3
基因名：

KCNRG
别名：

KCNRG antibody; CLLD4Potassium channel regulatory protein antibody; Potassium channel regulator antibody; Protein CLLD4 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Potassium channel regulatory protein (1-229AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes.
基因功能参考文献：
1. The haploinsufficiency of KCNRG might be relevant to the progression of chronic lymphocytic leukemia (CLL)and multiple myeloma(MM) at least in a subset of patients. PMID: 20237900
2. KCNRG is an ER-associated protein, which is proposed to regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes. PMID: 19968958
3. the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3; is a candidate for a B-cell chronic lymphocytic leukemia and prostate cancer tumor suppressor gene PMID: 12650944
4. Results suggest that genetic alterations and the expression of KCNRG might play an important role in the development and/or progression of a subset of hepatocellular carcinoma. PMID: 16819283
5. Autoantibodies to KCNRG were present in 7 of the 8 patients with respiratory symptoms in autoimmune polyendocrine syndrome type 1 PMID: 19251657
6. KCNRG suppresses K+ channel activity in human prostate cell line LNCaP. PMID: 12650944
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亚细胞定位：

Endoplasmic reticulum.
组织特异性：

Ubiquitous in normal tissues and expressed in some tumor tissues.
数据库链接：

HGNC: 18893

OMIM: 607947

KEGG: hsa:283518

STRING: 9606.ENSP00000324191

UniGene: Hs.660161