KCNH7 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) KCNH7 Polyclonal antibody
Uniprot No.：

Q9NS40
基因名：

KCNH7
别名：

KCNH7 antibody; ERG3Potassium voltage-gated channel subfamily H member 7 antibody; Ether-a-go-go-related gene potassium channel 3 antibody; ERG-3 antibody; Eag-related protein 3 antibody; Ether-a-go-go-related protein 3 antibody; hERG-3 antibody; Voltage-gated potassium channel subunit Kv11.3 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
基因功能参考文献：
1. we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a melanoma cell model PMID: 26942884
2. KCNH7 c.1181G>A had the highest enrichment among individuals with bipolar spectrum disorder (x2 5 7.3) and the strongest family-based association with bipolar 1 (P 5 0.021), bipolar spectrum (P 5 0.031) and any major affective disorder (P 5 0.016). PMID: 24986916
3. The recombinant wild-type ERG3 protein produced in HEK cells generates two prominent bands. When the entire CNBD of ERG3 protein was deleted, only an EndoH-sensitive band was generated, indicating that this band constitutes the immature species. PMID: 15961404
亚细胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily
组织特异性：

Expressed in prolactin-secreting adenomas.
数据库链接：

HGNC: 18863

OMIM: 608169

KEGG: hsa:90134

STRING: 9606.ENSP00000331727

UniGene: Hs.657413