Hpx Antibody, HRP conjugated

^{Rare Species}

产品详情

产品名称：

Rabbit anti-Rattus norvegicus (Rat) Hpx Polyclonal antibody
Uniprot No.：

P20059
基因名：

Hpx
别名：

Hpx antibody; Hemopexin antibody
宿主：

Rabbit
反应种属：

Rat
免疫原：

Recombinant Rat Hemopexin protein (24-460AA)
免疫原种属：

Rattus norvegicus (Rat)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
基因功能参考文献：
1. Data suggest that apo-hemopexin isolated from plasma exchibits low endogenous levels of tyrosine nitration in the peptide YYCFQGNQFLR in the heme-binding site of human hemopexin, which was similarly nitrated in rabbit and rat hemopexins; heme binding by hemopexin declined as tyrosine nitration proceeded in vitro. PMID: 28596380
2. Hemopexin was identified as upregulated protein in the small intestine exposed to indomethacin. PMID: 22486875
3. hemopexin mRNA was low or undetectable in livers of hypophysectomized rats, however, daily treatment with bovine growth hormone for 10 days restored hemopexin mRNA levels PMID: 12850285
4. intracellular calcium and protein kinase C activation are involved in the regulation of Hpx. PMID: 12850286
亚细胞定位：

Secreted.
蛋白家族：

Hemopexin family
组织特异性：

Expressed by the liver and secreted in plasma.
数据库链接：

KEGG: rno:58917

STRING: 10116.ENSRNOP00000024710

UniGene: Rn.2380