HSPA12A Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) HSPA12A Polyclonal antibody
Uniprot No.：

O43301
基因名：

HSPA12A
别名：

FLJ13874 antibody; Heat shock 70 kDa protein 12A antibody; heat shock 70kD protein 12A antibody; heat shock 70kDa protein 12A antibody; HS12A_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Heat shock 70 kDa protein 12A protein (2-231AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.
基因功能参考文献：
1. The genotype "A/G" of rs1665650 in HSPA12A gene was associated with a decreased risk of gastric cancer. PMID: 26302849
2. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC PMID: 25798051
3. We found that HSPA12A is expressed in the human brain and shows a neuron- and region-specific transcript distribution, with strongest expression in the frontal and occipital cortical regions. HSPA12A Mrna was significantly reduced in schizophrenia. PMID: 15601604
4. Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
5. Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241
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亚细胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Heat shock protein 70 family
组织特异性：

Widely expressed with highest levels in brain, kidney and muscle.
数据库链接：

HGNC: 19022

OMIM: 610701

KEGG: hsa:259217

STRING: 9606.ENSP00000358211

UniGene: Hs.648448