HSD17B14 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) HSD17B14 Polyclonal antibody
Uniprot No.：

Q9BPX1
基因名：

HSD17B14
别名：

HSD17B14 antibody; DHRS10 antibody; SDR3 antibody; SDR47C1 antibody; UNQ502/PRO47417-beta-hydroxysteroid dehydrogenase 14 antibody; 17-beta-HSD 14 antibody; EC 1.1.1.- antibody; 17-beta-hydroxysteroid dehydrogenase DHRS10 antibody; Dehydrogenase/reductase SDR family member 10 antibody; Retinal short-chain dehydrogenase/reductase retSDR3 antibody; Short chain dehydrogenase/reductase family 47C member 1 antibody
宿主：

Rabbit
反应种属：

Human, Mouse
免疫原：

Recombinant Human 17-beta-hydroxysteroid dehydrogenase 14 protein (1-270AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，HSD17B14 Antibody (CSB-PA859026HA01HU)，的标记方式是Non-conjugated。对于HSD17B14 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA859026HB01HU	HSD17B14 Antibody, HRP conjugated	ELISA
FITC	CSB-PA859026HC01HU	HSD17B14 Antibody, FITC conjugated
Biotin	CSB-PA859026HD01HU	HSD17B14 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB
推荐稀释比：

Application Recommended Dilution

WB 1:1000-1:5000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).
基因功能参考文献：
1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. PMID: 22792371
2. crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family PMID: 17067289
亚细胞定位：

Cytoplasm.
蛋白家族：

Short-chain dehydrogenases/reductases (SDR) family
组织特异性：

Highly expressed in brain, placenta, liver and kidney.
数据库链接：

HGNC: 23238

OMIM: 612832

KEGG: hsa:51171

STRING: 9606.ENSP00000263278

UniGene: Hs.18788