Your Good Partner in Biology Research

中文简体

CSF2｜ CTLA4｜ DLL3｜ EGFR｜ IL4｜ IL4R｜ LAG3｜ MSTN｜ NECTIN4｜ NT5E｜ SEZ6｜ TM4SF1｜ TNFSF13｜ TPO

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. HS3ST3B1 Antibody, HRP conjugated

HS3ST3B1 Antibody, HRP conjugated

说明书
  • 中文名称：
    HS3ST3B1兔多克隆抗体, HRP偶联
  • 货号：
    CSB-PA897580LB01HU
  • 规格：
    ￥880
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HS3ST3B1 Polyclonal antibody
  • Uniprot No.：
    Q9Y662
  • 基因名：
    HS3ST3B1
  • 别名：
    Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B), HS3ST3B1, 3OST3B1 HS3ST3B
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    HRP
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
    ELISA Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

相关产品

HS3ST3B1 antibodies

HS3ST3B1 Proteins

靶点详情

  • 功能：
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
  • 基因功能参考文献：
    1. The SNP rs28470223 results in decreased promoter activity of HS3ST3A1 and slightly higher HS3ST3A1 catalytic activity in vitro. PMID: 29718295
    2. These findings indicate that HS3ST3B1 is a novel regulator of TGF-beta-mediated EMT and is regulated by miR-218 in NSCLC. PMID: 29516954
    3. A genome-wide high-throughput siRNA screen revealed that KIR2DL4 recognition of cell-surface ligand(s) is directly regulated by heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1). PMID: 24127555
    4. Genetic variants of HS3ST3A1 and HS3ST3B1 are associated with Plasmodium falciparum parasitaemia. PMID: 22475533
    5. the results from this study unveiled a distinct function for 3-OST-3B1 as an Epithelial-mesenchymal transition inducer in cancer and provided a link between histone modification and Epithelial-mesenchymal transition modulation. PMID: 21709440
    6. HS3ST3B1 showed potent inhibitory effect on HBV replication. PMID: 20705311

    显示更多

    收起更多

  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 组织特异性：
    Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney.
  • 数据库链接：

    HGNC: 5198

    OMIM: 604058

    KEGG: hsa:9953

    STRING: 9606.ENSP00000354213

    UniGene: Hs.48384

Most popular with customers

产品中心
特别关注


X
九游平台-九游(中国) | 米兰体育-米兰体育（中国） | 开云手机在线登陆入口 | 江南官方体育网页版 | 开云网页版 | 开云官方在线入口 | 开云电子体育 | 开云官方链接 | 江南网页版页面登录 |