HFM1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) HFM1 Polyclonal antibody
Uniprot No.：

A2PYH4
基因名：

HFM1
别名：

HFM1 antibody; SEC3D1Probable ATP-dependent DNA helicase HFM1 antibody; EC 3.6.4.12 antibody; SEC63 domain-containing protein 1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Probable ATP-dependent DNA helicase HFM1 protein (121-420AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for crossover formation and complete synapsis of homologous chromosomes during meiosis.
基因功能参考文献：
1. Data suggest that HFM1 gene might be associated with primary ovarian insufficiency in Chinese population. PMID: 26679638
2. Exome sequencing of two Chinese sisters with primary ovarian insufficiency and their parents identified a shared compound heterozygous mutation in a meiotic gene, HFM1, which encodes a protein necessary for homologous recombination of chromosomes. PMID: 24597873
3. hHFM1 is the evolutionally conserved putative human DNA helicase, which may function as a modulator for genome integrity in germ-line tissues. PMID: 17286053
相关疾病：

Premature ovarian failure 9 (POF9)
蛋白家族：

Helicase family, SKI2 subfamily
组织特异性：

Preferentially expressed in testis and ovary.
数据库链接：

HGNC: 20193

OMIM: 615684

KEGG: hsa:164045

STRING: 9606.ENSP00000359454

UniGene: Hs.454818