HERC3 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) HERC3 Polyclonal antibody
Uniprot No.：

Q15034
基因名：

HERC3
别名：

HERC3 antibody; KIAA0032Probable E3 ubiquitin-protein ligase HERC3 antibody; EC 2.3.2.26 antibody; HECT domain and RCC1-like domain-containing protein 3 antibody; HECT-type E3 ubiquitin transferase HERC3 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Probable E3 ubiquitin-protein ligase HERC3 protein (1-200AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
基因功能参考文献：
1. HERC3 negatively regulates NF-kappaB signaling by enhancing RelA subunit degradation. PMID: 26476452
2. we found somatic mutations of HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B genes in gastric carcinoma and colorectal carcinomas with microsatellite instability PMID: 22124266
亚细胞定位：

Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
数据库链接：

HGNC: 4876

OMIM: 605200

KEGG: hsa:8916

STRING: 9606.ENSP00000264345

UniGene: Hs.35804