HECTD2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) HECTD2 Polyclonal antibody
Uniprot No.：

Q5U5R9
基因名：

HECTD2
别名：

FLJ16050 antibody; FLJ37306 antibody; HECD2_HUMAN antibody; HECT domain containing 2 antibody; HECT domain containing protein 2 antibody; HECT domain-containing protein 2 antibody; Hectd2 antibody; OTTHUMP00000020086 antibody; OTTHUMP00000038605 antibody; Probable E3 ubiquitin protein ligase HECTD2 antibody; Probable E3 ubiquitin-protein ligase HECTD2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Probable E3 ubiquitin-protein ligase HECTD2 protein (674-776AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.; (Microbial infection) Catalyzes ubiquitination of Botulinum neurotoxin A light chain (LC) of C.botulinum neurotoxin type A (BoNT/A).
基因功能参考文献：
1. A major biological consequence of upregulation of miR-221 is reprogramming of androgen receptor signaling via downregulation of HECTD2 and RAB1A. PMID: 23770851
2. HECTD2 polymorphisms are not associated with genetic susceptibility to sporadic Creutzfeldt-Jakob disease in a Korean population PMID: 21335971
3. HECTD2 haplotypes are associated with the susceptibility to human prion diseases. PMID: 19214206
4. The common haplotypes of HECTD2, tagged by rs12249854, are not associated with susceptibility to late onset Alzheimer's disease PMID: 19754925
数据库链接：

HGNC: 26736

KEGG: hsa:143279

STRING: 9606.ENSP00000298068

UniGene: Hs.596096