HCFC1R1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) HCFC1R1 Polyclonal antibody
Uniprot No.：

Q9NWW0
基因名：

HCFC1R1
别名：

HCF 1 beta propeller interacting protein antibody; HCF-1 beta-propeller-interacting protein antibody; HCF1 beta propeller interacting protein antibody; HCFC1R1 antibody; Host cell factor C1 regulator 1 (XPO1 dependent) antibody; Host cell factor C1 regulator 1 antibody; HPIP antibody; HPIP_HUMAN antibody; Inhibitor of four 2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Host cell factor C1 regulator 1 protein (1-119AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
基因功能参考文献：
1. HPIP overexpression is an independent predictor of platinum-based chemotherapy resistance in epithelial ovarian neoplasms. PMID: 27818289
2. HPIP promotes thyroid cancer cell growth, migration and epithelial mesenchymal transformation through activating PI3K/AKT signaling pathway. PMID: 26463629
3. HPIP is upregulated in colorectal cancer and regulates colorectal cancer cell proliferation, apoptosis and invasion PMID: 25800793
4. HPIP regulates HCF-1 activity by modulating its subcellular localization PMID: 12235138
亚细胞定位：

Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.
组织特异性：

Widely expressed.
数据库链接：

HGNC: 21198

KEGG: hsa:54985

UniGene: Hs.423103