H2AFJ Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) H2AFJ Polyclonal antibody
Uniprot No.：

Q9BTM1
基因名：

H2AFJ
别名：

H2AFJ antibody; Histone H2A.J antibody; H2a/j antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Histone H2A.J protein (2-129AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
基因功能参考文献：
1. Histone variant H2A.J (H2A.J) accumulates in senescent fibroblasts with DNA damage. PMID: 28489069
2. The antimicrobial protein buforin I results from proteolytic cleavage of the histone protein H2A in the stomach. PMID: 21178486
3. In this paper, the authors identified and cloned the H2AFJ gene on chr 12 and used it as a control for studying two macroH2A genes. PMID: 11331621
亚细胞定位：

Nucleus. Chromosome.
蛋白家族：

Histone H2A family
数据库链接：

HGNC: 14456

KEGG: hsa:55766

STRING: 9606.ENSP00000373730

UniGene: Hs.524280